Anemia Aguda
con Oxigenoterapia Hiperbarica

¿TRATAMIENTO DE ANEMIA: CÓMO PUEDE AYUDAR LA CÁMARA HIPERBÁRICA EN EL POR PÉRDIDA DE SANGRE AGUDA?

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Algunos de los beneficios de la OHB en el tratamiento de la anemia o pérdida de sangre aguda pueden incluir:

  1. Aumento del suministro de oxígeno: La OHB implica la inhalación de oxígeno puro en un entorno de alta presión, lo que aumenta significativamente la cantidad de oxígeno que la sangre puede transportar. 

  2. Aumenta glóbulos rojos: Esto es beneficioso cuando la anemia resulta en niveles bajos de oxígeno en sangre, ya que la OHB ayuda a compensar esta deficiencia, mejorando así el suministro de oxígeno a los tejidos y órganos del cuerpo.

  3. Promoción de la cicatrización de heridas: En situaciones en las que la anemia es el resultado de una cirugía o una lesión traumática que requiere reparación de tejidos, la OHB puede acelerar la cicatrización de heridas al aumentar el flujo sanguíneo y la disponibilidad de oxígeno en la zona afectada.

  4. Proteccion de organos vitales: La OHB puede proporcionar oxígeno adicional para el corazón y el cerebro, dos de los órganos más grandes consumidores de oxígeno en el cuerpo

  5. Reducción del riesgo de hipoxia: La OHB puede ayudar a prevenir la hipoxia, que es la falta de oxígeno en los tejidos del cuerpo, que a veces se produce como resultado de la anemia grave.

  6. Mejora de la supervivencia: Estudios en animales y casos clínicos en humanos respaldan la idea de que la OHB puede aumentar la supervivencia en situaciones críticas en las que la transfusión de sangre no es factible

LA TERAPIA HIPERBÁRICA pARA EL TRATAMIENTO DE ANEMIA

La oxigenoterapia hiperbárica (OHB) es una terapia que puede ayudar a las personas con anemia severa cuando no pueden recibir transfusiones de sangre o eligen no hacerlo por razones médicas o religiosas. En la anemia severa, la sangre no transporta suficiente oxígeno, lo que puede causar problemas graves.

La OHB implica respirar oxígeno puro bajo presión en una cámara especial. Esto aumenta la cantidad de oxígeno que la sangre puede llevar. Ayuda a rectificar la falta de oxígeno y mejora la entrega de oxígeno al corazón y al cerebro, que son órganos que necesitan mucho oxígeno.

Estudios en animales y pacientes han respaldado su eficacia. Se considera una opción de tratamiento cuando la transfusión de sangre no es posible. La OHB se ajusta a pautas basadas en evidencia médica y puede ayudar a corregir la falta de oxígeno en el cuerpo en casos de anemia severa, mejorando la salud y el bienestar del paciente.

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CÓMO SIRVE LA TERAPIA EN CÁMARA HIPERBÁRICA PARA LA ANEMIA AGUDA

Más detallado y estudios de soporte Usando presiones arriba de 2.0 ATA​
Investigaciónes y Fuentes

Liceaga, D. E. (2014). GUÍAS CLÍNICAS DE DIAGNÓSTICO Y TRATAMIENTO DEL SERVICIO DE CÁMARA HIPERBÁRICA. Ciudad de Mexico: Hospital General de Mexico.

Undersea and Hyperbaric Medical Society. (2021). Indications for Hyperbaric Oxygen Therapy. Retrieved from https://www.uhms.org/resources/hbo-indications.html

https://www.uhms.org/7-severe-anemia.html

Chapter 13: Severe Anemia
Keith W. Van Meter MD
REFERENCES
1. Van Slyke DD, Neill JM. The determination of gases in blood and other solutions by vacuum extraction and
manomet- ric measurement. J Biol Chem. 1924;61:523-573.
2. Chance EM, Chance B. Oxygen delivery to tissue: calculation of oxygen gradient in the cardiac cell. Adv Exp Med
Biol. 1988;222:69-75.
3. Fick A. Uber die messung des blut quantums in der herzventrikeln. SB Phys-Med Ges Wurzburg. 1870:16.
4. Shoemaker WC, Appel PL, Kram HB. Tissue oxygen debt as a determinant of lethal and nonlethal post-operative
organ failure. Crit Care Med. 1988;16:1117-1120.
5. Goodnough LT, Schander A, Brecher ME. Transfusion medicine: looking into the future. Lancet. 2003;361:161-
169.
6. Johnson JL, Moore EE, Gonzalez RJ, et al. Alteration of the post-injury hyperinflammatory response by means of
resuscitation with a red cell substitute. J Trauma. 2003;54:133-140.
7. Vamvakas EC. Transfusion associated cancer recurrence and post-operative infection: meta-analysis of randomized
controlled clinical trials. Transfusion. 1996;36:175-186.
8. Winslow RM. Blood substitutes. Curr Opin Hematol. 2002;9:146-151.
9. Cohn C, Cushing M. Oxygen therapeutics: perfluorocarbons and blood substitute safety. Crit Care Med. 2009;25:
399-414.
10. Kindwall EP, editor. Hyperbaric oxygen therapy: a committee report. Bethesda, MD: Undersea and Hyperbaric
Medical Society; 1977.
11. Hampson NB, editor. Hyperbaric oxygen therapy: a committee report. Bethesda, MD: Undersea and Hyperbaric
Medical Society; 1999. Pp. 35-36.
12. Hart GB. Hyperbaric oxygen and exceptional blood loss anemia. In: Kindwall EP, Whelan HT, editors. Hyperbaric
medicine practice. 2nd ed. revised. Flagstaff, AZ: Best Publishing Co.; 2002. Pp. 741-751.
13. DeBets D, Theunissen S, Devriendt J, et al. The normobaric oxygen paradox: does it increase hemoglobin. Diving
and Hyperbar Med. 2012;42(2):67-71.
14. Brozak J, Grande F. Body composition and basal metabolism in man correlation analysis versus physiologic
approach. Human Biol. 1955;27:22-31.
15. Boerema I, Meyne NG, Brummelkamp WH, et al. Life without blood. Arch Chir Neerl. 1959;11:70-84.
16. McLoughlin PL, Cope TM, Harrison JC. Hyperbaric oxygen therapy in management of severe acute anemia in a
Jehovah’s witness. Anesthesia. 1999;54:879-898.
17. Cummins RO, Hazinski MF, Kerber RE, et al. Low-energy biphasic waveform defibrillation: evidence-based review
applied to emergency cardiovascular care guidelines. Circulation. 1998;97:1654-1667.
18. Burnet W, Clark RG, Duthie HL, et al. The treatment of shock by oxygen under pressure. Scot Med J. 1959;4:535-
538.
19. Cowley RA, Attar S, Esmond WG, et al. Electrocardiographic and biochemical study in hemorrhagic shock in dogs
treated with hyperbaric oxygen. Circulation. 1963;27:670-675.
20. Blair E, Henning G, Esmond WG, et al. The effect of hyperbaric oxygenation (OHP) on three forms of shock –
traumatic, hemorrhagic, and septic. J Trauma. 1964;4:652-663.
21. Clark RG, Young DG. Effects of hyperoxygenation and sodium bicarbonate in hemorrhagic hypotension. Brit J
Surg. 1965;52:705-708.
22. Cowley RA, Attar S, Blair E, et al. Prevention and treatment of shock by hyperbaric oxygenation. Ann NY Acad Sci.
1965;117:673-683.
23. Elliot DP, Paton BC. Effect of 100% oxygen at 1 and 3 atmospheres on dogs subjected to hemorrhagic hypotension.
Surg. 1965;57:401-408.
24. Attar S, Scanlan E, Cowley RA. Further evaluation of hyperbaric oxygen in hemorrhagic shock. In: Brown IW, Cox
B, editors. Proceedings of the third international congress on hyperbaric medicine. Washington DC: NAS/NRC;
1965. Pp. 417-424.
25. Jacobson YG, Keller ML, Mundth ED, et al. Hyperbaric oxygen therapy in experimental hemorrhagic shock. In:
Brown IW, Cox B, editors. Proceedings of the third international congress on hyperbaric medicine. Washington DC:
NAS/NRC; 1966. Pp. 425-431.
26. Jacobson YG, Keller ML, Mundth ED, et al. Hemorrhagic shock: influence of hyperbaric oxygen on metabolic
parameters. Calif Med. 1966;105:93-96.
27. Navarro RU, Ferguson CC. Treatment of experimental hemorrhagic shock by the combined use of hyperbaric
oxygen and low-molecular weight dextran. Surg. 1968;63:775-781.
Copyright © 2019 Undersea and Hyperbaric Medical Society, Inc.
28. Doi Y, Onji Y. Oxygen deficit in hemorrhagic shock under hyperbaric oxygen. In: Wada J, Iwa JT, editors.
Proceedings of the fourth international congress on hyperbaric medicine. Baltimore, MD: Williams and Wilkins;
1970. P. 181-184.
29. Necas E, Neuwirt J. Lack of erythropoietin in plasma of anemic rats exposed to hyperbaric oxygen. Life Sci.
1969;8:1221-1228.
30. Oda T, Takeori M. Effect of viscosity of the blood on increase in cardiac output following acute hemodilation. In:
Wada J, Iwa JT, editors. Proceedings of the fourth international congress on hyperbaric medicine. Baltimore, MD:
Williams and Wilkins; 1970. Pp. 191-196.
31. Norman JN. Hemodynamic studies in total blood replacement. Biblio Haema. 1975;41:203-208.
32. Luenov AN, Yakovlev VN. Role played by cerebral nitrogen metabolism in the mechanism of the therapeutic oxygen
effects under high pressure in the hemorrhagic shock. Biull Eksp Biol Med. 1977;83:418-420.
33. Gross DR, Moreau PM, Jabor M, Welch DW, Fife WP. Hemodynamic effects of dextran-40 on hemorrhagic shock
during hyperbaria and hyperbaric hyperoxia. Aviat Space Environ Med. 1983;54:413-419.
34. Gross DR, Moreau PM, Chaikin BN, et al. Hemodynamic effects of lactated Ringers’ solution on hemorrhagic shock
during exposure to hyperbaric air and hyperbaric hyperoxia. Aviat Space Environ Med. 1983;54:701-708.
35. Gross DR, Dodd KT, Welch DW, Fife WP. Hemodynamic effects of 10% dextrose and of dextran-70 on
hemorrhagic shock during exposure to hyperbaric air and hyperbaric hyperoxia. Aviat Space Environ Med.
1984;55:1118-1128.
36. Bitterman H, Reissman P, Bitterman N, et al. Oxygen therapy in hemorrhagic shock. Circ Shock. 1991;33:183-191.
37. Wen-Ren L. Resection of aortic aneurysms under 3 ATA of hyperbaric oxygenation. In: Bakker DJ, Cramer JS,
editors. Proceedings of the tenth international congress of hyperbaric medicine. Flagstaff, AZ: Best Publishing Co.;
1992. Pp. 94-95.
38. Adir Y, Bitterman N, Katz E, et al. Salulary consequences of oxygen therapy or long-term outcome of hemorrhagic
shock in awake, unrestrained rats. Undersea Hyperb Med. 1995;22:23-30.
39. Yamashita M, Yamashita M. Hyperbaric oxygen treatment attenuates cytokine induction after massive hemorrhage.
Am J Physiol Endocrin Metab. 2000;28:E811-E816.
40. Boerema I, Meyne NG, Brummelkamp WH, et al. Life without blood: a study of the influence of high atmosphere
pressure and hypothermia on dilution of the blood. J Cardiovasc Surg. 1960;1:133-146.
41. Attar S, Esmond WG, Cowley RA. Hyperbaric oxygenation in vascular collapse. J Thoracic Cardiovasc Surg.
1962;42:759-770.
42. Trytyshnikov IM. Effect of acute massive blood loss during hyperbaric oxygen therapy on nucleic and metabolism in
the albino rat liver. Biull Eksp Biol Med. 1974;77:23-25.
43. Frank HA, Fine J. Traumatic shock V: a study of the effect of oxygen on hemorrhagic shock. J Clin Invest. 1943;22:
305-314.
44. Whalen RE, Moor GF, Mauney FM, et al. Hemodynamic responses to “Life Without Blood.” In: Brown IW, Cox B,
editors. Proceedings of the third international congress on hyperbaric medicine. Washington DC: NAS/NRC; 1965.
Pp. 402-408.
45. Barkova EN, Petrov AV. The effect of oxygen barotherapy on erythropoeisis in the recuperative period following
hemorrhagic collapse. Buill Eksp Biol Med. 1976;81:156-158.
46. Marzella L, Yin A, Darlington D, et al. Hemodynamic responses to hyperbaric oxygen administration in a rat model
of hemorrhagic shock. Circ Shock. 1992;37:12.
47. Cancer.Net. Levels of evidence: explanation in therapeutic studies (PDQ). Internet Service of the National Cancer
Institute, 1999.
48. Barton S, editor. Clinical evidence. London: BMJ Publishing Group; 2001.
49. Wiggers CJ, Werle JM. Exploration of method for standardizing hemorrhagic shock. Proc Soc Exper Biol Med.
1942;49:604.
50. Bellamy RF, Maningas PA, Wenger BA, et al. Current shock models and clinical correlations. Ann Emerg Med.
1986;15:1392-1395.
51. Ledingham IM. Hyperbaric oxygen in shock. Anes Clin. 1969;7:819-839.
52. Amonic RS, Cockett ATK, Lonhan PH, et al. Hyperbaric oxygen therapy in chronic hemorrhagic shock. JAMA.
1969;208:2051-2054.
53. Hart GB. Exceptional blood loss anemia. JAMA. 1974;228:1028-1029.
54. Myking O, Schreinen A. Hyperbaric oxygen in hemolytic crisis. JAMA. 1974;227:1161-1162.
55. Hart GB, Lennon PA, Strauss MB. Hyperbaric oxygen in exceptional acute blood loss anemia. J Hyperbar Med.
1987;2:205-210.
Copyright © 2019 Undersea and Hyperbaric Medical Society, Inc.
56. Meyerstein N, Mazor D, Tsach T, et al. Resistance of human red blood cells to hyperbaric oxygen under therapeutic
conditions. J Hyperbar Med. 1989;4:1-5.
57. Young BA, Burns JR. Management of the severely anemic Jehovah’s Witness. Ann Int Med. 1992;119:170.
58. Van Meter KW. A systematic review of the literature reporting the application of hyperbaric oxygen in the treatment
of exceptional blood loss anemia: an evidence-based approach. Undersea Hyperb Med. 2005;32(1):61-83.
59. Hillard JR. Severe claustrophobia in a patient requiring hyperbaric oxygen treatment. Psychosomatics. 1990;31:
107-108.
60. Ross ME, Yolton DP, Yolton RL, et al. Myopia associated with hyperbaric oxygen therapy. Optometry and Vision
Sci. 1996;73:487-494.
61. Ueno S, Sakoda M, Kurahara H, et al. Safety and efficacy of early post-operative hyperbaric oxygen therapy with
restriction of transfusionsin patient with HCC who have undergone partial hepatectomy. Arch Surg. 2011;396:
99-106.
62. Blanchard J, Toma A, Bryson P, et al. Middle ear barotrauma in patients undergoing hyperbaric oxygen therapy. Clin
Otolaryn. 1996;21:400-403.
63. Youngberg JT, Myers AM. Complications from hyperbaric oxygen therapy. Ann Emerg Med. 1990;19:1356-1357.
64. Van Meter KW, Harch PG. HBO in emergency medicine. In: Jain KK, editor. Textbook of hyperbaric medicine.
Cambridge, MA: Hogrefe & Huber Publishers; 1996. Pp. 453-481.
65. Van Meter KW. Hyperbaric oxygen therapy as an adjunct to pre-hospital advanced life support. Surg Technol Int.
2011 Dec 1;XXI:61-73.
66. Donat A, Damani E, Zuccan S, et al. Effects of short-term hyperoxia on erythropoietin levels and microcirculation
in critically ill patients: a prospective, observational pilot study. MMC Anesthesiology 2017;17:49-59
67. Van Meter K. Van Meter KW. The effect of hyperbaric oxygen on severe anemia. Undersea Hyperb Med.
2012;39(5):937-42.
68. Saa P, Proctor M, Foster-Getal. Investigational testing for Zika virus among US blood donors. NEJM
2018;378:1778-1788.
69. Harrington T, Kuehnent MJ, Kamel H, et al. West Nile virus infection transmitted by blood transfusion.
Transfusion 2004;3:1018-1022.
70. Graffeo C, Dishong W. Severe blood loss anemia in a Jehovah’s Witness treated with adjunctive hyperbaric oxygen
therapy. American Journal of Emergency Medicine. 2013;31:756.e3-756.e4.
71. Gutierrez G, Brotherton J. Management of severe anemia secondary to menorrhagia in a Jehovah’s Witness: a case
report and treatment algorithm. American Journal of Obstetrics & Gynecology. 2011;205(2):e5-8.
72. Wright JK, Ehler W, McGlasson DL, Thompson W. Facilitation of recovery from acute blood loss with hyperbaric
oxygen. Archives of Surgery. 2002;137:850-853.